Welcome to Meltome Atlas!

This R-Shiny App allows interactive exploration of the dataset published by Jarzab et al., (2020), Nat. Methods.

The different tabs lead you to exploring the either the comparison of thermal proteome profiles across various species or across different human cell lines and cell types.

Have fun!

Plot proteins of interest in different species

Select species and a protein
Drosophila melanogaster SII lysate
Mus musculus BMDC lysate
Homo sapiens Jurkat cells

Plot protein of interest in different human cell lines

Select cell lines and a protein
Jurkat
U937
pTcells
JAK1

Plot different proteins of interest in a desired cell line

Select proteins and a cell line
Jurkat
AAAS
ABL1
BCR

Scatterplot of protein melting points in desired cell lines

Select cell lines
Jurkat
HepG2
cross-species
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